In a large skillet, warm olive oil and saute chicken, mushrooms, onion and garlic. Stir in flour until blended and add in Alfredo sauce. Bring to a boil. Reduce heat a simmer without a lid for 5 min. Meanwhile in a separate bowl combine cottage cheese, egg, 1/4 cup parmesan cheese, Italian seasoning, and parsley.
Spread 1/2 cup of chicken mixture in an 8 in x 4 in. loaf pan coated with cooking spray. Layer 2 lasagna noodles (trimmed to fit pan), half the cheese mixture, 3/4 cup chicken mixture and 3/4 cup mozzarella cheese. Sprinkle with remaining parmesan cheese. Repeat layers.
Cover and bake at 350°F for 30 min. Uncover and bake for 10 more min. Let stand for 10 min. before serving.