Combine cream cheese, granulated sugar and margarine, mixing at medium speed on electric mixer until well blended. Blend in eggs and vanilla. Add combined dry ingredients alternately with milk, mixing well after each addition.
Pour batter into greased and floured 13 X 9-inch baking pan. Sprinkle with Streusel Mixture.
Bake at 350 degrees F for 30 minutes or until wooden pick inserted in center comes out clean.
Streusel Mixture: Combine nuts, brown sugar, flour and cinnamon; cut in margarine until mixture resembles coarse crumbs.